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DMT-2'-O-TBDMS-U-CE Phosphoramidite Application_Diagnostics Commonly used in chemically modified

SKU: 67834883583

4.2
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Description

Commonly used in chemically modified small interfering RNA (siRNA) to enhance stability

TBDMS deprotection can be achieved using fluoride reagents (e

High purity

color: #3361ac

" Tetrahedron letters 22

DMT-2'-O-TBDMS-U-CE Phosphoramidite Application_Diagnostics Commonly used in chemically modifiedDMT 2' O TBDMS U CE Phosphoramidite is a protected ribonucleoside building block used for solid phase RNA oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a 2' O tert butyldimethylsilyl (TBDMS) protecting group for 2' hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a uracil. TBDMS offers excellent stability for protecting 2' hydroxyl of ribonucleosides during acid

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