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DMT-2'-F-dU-CE Phosphoramidite Amount/Package:5g / 240mL screwed bottle } DMT-2'-O-Me-I-CE Phosphoramidite is a

SKU: 5230542051

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Description

} DMT-2'-O-Me-I-CE Phosphoramidite is a 2'-OMe phosphoramidite monomer used for solid-phase oligonucleotide synthesis

[1] Svitkin

mildly alkaline environment (typically pH 7

and a 2'-O-methyl (2'-OMe) ribose modification

" Molecular Therapy Nucleic Acids 12 (2018): 530-542

DMT-2'-F-dU-CE Phosphoramidite Amount/Package:5g / 240mL screwed bottle } DMT-2'-O-Me-I-CE Phosphoramidite is aDMT 2 F dU CE Phosphoramidite is a 2' fluoro (2' F) phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a 2' F modification on the sugar of deoxyuridine (dU), a 5 dimethoxytrityl (DMT) group for 5' hydroxyl protection, and a cyanoethyl (CE) protecting group on phosphite. Synthesis of RNA oligonucleotides using 2' F phosphoramidite increases the nuclease resistance and binding affinity of duplexes formed with

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