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Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine)
which binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells
86 kDa subunit of Ku antigen
Species SARS-CoV-2 Accession P0DTC9 Amino Acid Sequence MSDNGPQNQRNALRITFGGPSDSTGSNQNGGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNSANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSKRTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSRADSTQAGGGSHHHHHHHH Expression System E
H20 and 1-5 μl Endo H
HMGB1/HMG1 His Tag Protein, Mouse Size:500μg Trastuzumab emtansine (Ado-Trastuzumab emtansine) isProduct Specification Species Mouse Synonyms High mobility group protein 1 (HMG 1); Hmgb1; Hmg 1; Hmg1; HMG3, SBP 1 Accession P63158 Amino Acid Sequence Met1 Glu215 with His tag at the C Terminus Expression System HEK293 Molecular Weight 30 35kDa (Reducing) Purity 95% by SDS PAGE & 90% by SEC HPLC Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1